Dr. Raffaele received his B.A. in philosophy from Princeton University and his M.D. from Drexel University Medical School in 1989. He trained at The New York Hospital/Cornell University Medical Center and was formerly a clinical assistant professor of medicine at Dartmouth Medical School.
Dr. Raffaele is board certified in internal medicine, a member of the Endocrine Society, and a diplomat of the American Board of Anti-Aging Medicine. In 1997, he co-founded PhysioAge Medical Group, where he exclusively practiced age-management medicine, focusing on personalized hormone optimization and physiological age assessment.
In 2007, he co-founded PhysioAge Systems, a web-based biomarker data collection and reporting system (now used by age management practices worldwide) to assess, monitor, and communicate to patients the effectiveness of their treatments.
Since 2009, he has been involved in clinical telomere biology research and published three studies on the effects of oral telomerase activators on normal aging adults. He has lectured nationally and internationally on the clinical application of telomere biology.
In 2015 he founded Raffaele Medical Group. He regularly blogs about telomere biology, hormone optimization, and biomarkers of aging on DrRaffaele.com and PhysioAge.com.